The Alpecin-Fenix and Bahrain Victorious teams also withdrew, one day after the Jumbo-Visma squad left the eight-day race, which finishes Sunday.
“In the interest of the health of all riders and staff at the (Tour de Suisse), leaving the race is considered the most sensible decision by the team management and medical staff,” Alpecin-Fenix said.
Four positive tests, including Rigoberto Uran, were detected among the Education First squad in Friday morning tests.
“We have decided to give the option of starting to the two remaining riders, Neilson Powless and Jonas Rutsch, with the consent of our medical staff,” the Education First team said.
Marc Hirschi of UAE Team Emirates also tested positive and is out of the race, while his roommate, Joel Suter, was withdrawn as a precaution, the team said.
“Unfortunately, like many other teams we have also had a surge in COVID-19 cases,” UAE team medical director Adrian Rotunno said.
Tour de Suisse is one of the last events to prepare for the Tour de France, which starts in two weeks.